Pancreas

The pancreas is a thin, 15cm long organ that lies behind the stomach and under the liver. It is a vital organ with two crucial roles — helping the body digest food and making hormones that control blood sugar levels.

The pancreas has two main functions. Firstly, it helps the body break down, digest and absorb food. Secondly, it makes hormones that help control your blood sugar levels.

The pancreas is made up of glandular tissue and ducts (passages for body substances to flow through). These ducts help fluid from the pancreas flow into the duodenum (part of the small intestine).

The pancreas is made up of 2 types of cells.

1. Endocrine cells (Islets of Langerhans): these cells are responsible for the production of hormones such as glucagon and insulin which work together to regulate your body's blood sugar level.
2. Exocrine cells (acinar cells): these cells release digestive enzymes which help break down food so your body can absorb and utilise the nutrients.

Cells in your pancreas produce and release digestive enzymes into your duodenum, which is the start of the small intestine. In the duodenum, the digestive enzymes break down partially-digested food from the stomach.

A small part of the pancreas makes hormones that help control blood sugar levels. This part has alpha cells (which make glucagon) and beta cells (which make insulin). Glucagon and insulin work together to keep your blood glucose level steady.

Common diseases that can affect the pancreas include:

• pancreatitis — inflammation of the pancreas, which can be caused by gall bladder disease and excessive alcohol use
• diabetes — destruction or loss of beta cells can mean the pancreas doesn't produce enough insulin for blood sugar control
• cystic fibrosis — is associated with thick, sticky mucus, and this can prevent digestive enzymes being released into the duodenum
• pancreatic cancer — cancer of the pancreas

Symptoms associated with problems with the pancreas include:

• abdominal pain and tenderness
• nausea
• loss of appetite
• jaundice (yellowing of skin and eyes)
• foul-smelling poo
• fever
• weight loss

Diet and lifestyle are important for maintaining a healthy pancreas. Here are some examples:

• Reducing your alcohol intake can reduce your risk of developing pancreatitis and diabetes.
• If you smoke, quitting can reduce your risk of developing pancreatic cancer. Smokers are 2 to 3 times more likely to develop pancreatic cancer than non-smokers.

The National Pancreas Foundation will provide you with information on how the pancreas works and various medical conditions associated with the pancreas.

Read the Our mob and cancer (Opens in new tab) sheet to learn more on pancreatic cancer for Aboriginal and/or Torres Strait Islander people.

Read the Cancer Council's guide to best cancer care on pancreatic cancer (Opens in new tab) — available in English (Opens in new tab) and a range of community languages (Opens in new tab).

You can also call healthdirect on 1800 022 222 at any time to speak to a registered nurse (known as NURSE-ON-CALL in Victoria) for more information and advice.